The use of modified polymeric polyhipe as an immobilized cell matrix
Utilization of modified-polyHIPE polymer matrix in the immobilization cell system is probably can substitute conventional cell matrix. The confined microenvironment was designed to promote the bacterium growth and its metabolic activity. The applied forced-flow seeding technique yielded a more un...
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iium-209932012-07-05T04:19:36Z http://irep.iium.edu.my/20993/ The use of modified polymeric polyhipe as an immobilized cell matrix Jimat, Dzun Noraini Azmi, Azlin Suhaida TP248.13 Biotechnology Utilization of modified-polyHIPE polymer matrix in the immobilization cell system is probably can substitute conventional cell matrix. The confined microenvironment was designed to promote the bacterium growth and its metabolic activity. The applied forced-flow seeding technique yielded a more uniform distribution of cells within the polymeric support, which also helps to improve nutrient transport. This also prevents significant growth of cells around the outer surface of matrix. The microstructure of the matrix with respect to its physico-chemical characteristics, which include appropriate pore and interconnect sizes as well as surface chemistry (i.e. hydrophobic, hydrophilic), are very important with respect to the flow of nutrients and waste material and also for cell migration. As a result, the developed immobilized matrix can be performed effectively and essential in the area of bioprocess development specifically for microbial fermentations. IIUM Press 2011 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/20993/1/the_use_of_modified_-_C37.pdf Jimat, Dzun Noraini and Azmi, Azlin Suhaida (2011) The use of modified polymeric polyhipe as an immobilized cell matrix. In: Current research and development in biotechnology engineering at IIUM. IIUM Press, Kuala Lumpur, pp. 297-305. ISBN 9789674181444 http://rms.research.iium.edu.my/bookstore/default.aspx |
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Online Access |
language |
English |
topic |
TP248.13 Biotechnology |
spellingShingle |
TP248.13 Biotechnology Jimat, Dzun Noraini Azmi, Azlin Suhaida The use of modified polymeric polyhipe as an immobilized cell matrix |
description |
Utilization of modified-polyHIPE polymer matrix in the immobilization cell system is
probably can substitute conventional cell matrix. The confined microenvironment was
designed to promote the bacterium growth and its metabolic activity. The applied forced-flow
seeding technique yielded a more uniform distribution of cells within the polymeric support,
which also helps to improve nutrient transport. This also prevents significant growth of cells
around the outer surface of matrix. The microstructure of the matrix with respect to its
physico-chemical characteristics, which include appropriate pore and interconnect sizes as
well as surface chemistry (i.e. hydrophobic, hydrophilic), are very important with respect to
the flow of nutrients and waste material and also for cell migration. As a result, the developed
immobilized matrix can be performed effectively and essential in the area of bioprocess
development specifically for microbial fermentations. |
format |
Book Chapter |
author |
Jimat, Dzun Noraini Azmi, Azlin Suhaida |
author_facet |
Jimat, Dzun Noraini Azmi, Azlin Suhaida |
author_sort |
Jimat, Dzun Noraini |
title |
The use of modified polymeric polyhipe as an immobilized cell matrix |
title_short |
The use of modified polymeric polyhipe as an immobilized cell matrix |
title_full |
The use of modified polymeric polyhipe as an immobilized cell matrix |
title_fullStr |
The use of modified polymeric polyhipe as an immobilized cell matrix |
title_full_unstemmed |
The use of modified polymeric polyhipe as an immobilized cell matrix |
title_sort |
use of modified polymeric polyhipe as an immobilized cell matrix |
publisher |
IIUM Press |
publishDate |
2011 |
url |
http://irep.iium.edu.my/20993/ http://irep.iium.edu.my/20993/ http://irep.iium.edu.my/20993/1/the_use_of_modified_-_C37.pdf |
first_indexed |
2023-09-18T20:31:45Z |
last_indexed |
2023-09-18T20:31:45Z |
_version_ |
1777408782017495040 |