Blood pressure variability in patients with diabetes mellitus

Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to...

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Main Authors:	Mokhtar, Rafidah Hanim, Ayob, Azizi, Mohd Noor, Noriah
Format:	Article
Language:	English
Published:	SAGE Publications 2010
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/1/blood_pressure_variability_in_patients.pdf

id	iium-19015
recordtype	eprints
spelling	iium-190152016-11-12T04:03:37Z http://irep.iium.edu.my/19015/ Blood pressure variability in patients with diabetes mellitus Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah RC Internal medicine Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to compare blood pressure variability and arterial compliance in patients with type 2 diabetes mellitus and controls matched for sex, age, and weight. Arterial compliance was measured and noninvasive 24-h ambulatory blood pressure monitoring was performed in 18 diabetic patients and 18 controls. There was significantly higher 24-h systolic blood pressure variability (17.7 ± 6.8 vs. 14.6 ± 2.6 mm Hg), diastolic blood pressure variability (15.6 ± 7.1 vs. 11.4 ± 3.1 mm Hg), and mean arterial blood pressure variability (14.8 ± 7.0 vs. 11.1 ± 2.9) in diabetic patients. Systolic, diastolic, and mean arterial blood pressure variability was significantly higher during daytime but not night time in diabetic patients compared to controls. Diabetic patients also had significantly reduced small artery compliance, but no differences in large artery compliance, cardiac output, or systemic vascular resistance. The findings suggest that hyperglycemia may affect the compliance of the vascular system, resulting in high blood pressure fluctuations. SAGE Publications 2010-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/19015/1/blood_pressure_variability_in_patients.pdf Mokhtar, Rafidah Hanim and Ayob, Azizi and Mohd Noor, Noriah (2010) Blood pressure variability in patients with diabetes mellitus. Asian Cardiovascular and Thoracic Annals , 18 (4). pp. 344-348. ISSN 0218-4923 http://asianannals.ctsnetjournals.org/cgi/content/abstract/18/4/344
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah Blood pressure variability in patients with diabetes mellitus
description	Reduced arterial compliance in patients with diabetes mellitus has been shown in several studies, but it has not been significantly associated with either atherosclerosis or vessel wall thickness. Blood pressure variability is still poorly explored in diabetic patients. The aim of this study was to compare blood pressure variability and arterial compliance in patients with type 2 diabetes mellitus and controls matched for sex, age, and weight. Arterial compliance was measured and noninvasive 24-h ambulatory blood pressure monitoring was performed in 18 diabetic patients and 18 controls. There was significantly higher 24-h systolic blood pressure variability (17.7 ± 6.8 vs. 14.6 ± 2.6 mm Hg), diastolic blood pressure variability (15.6 ± 7.1 vs. 11.4 ± 3.1 mm Hg), and mean arterial blood pressure variability (14.8 ± 7.0 vs. 11.1 ± 2.9) in diabetic patients. Systolic, diastolic, and mean arterial blood pressure variability was significantly higher during daytime but not night time in diabetic patients compared to controls. Diabetic patients also had significantly reduced small artery compliance, but no differences in large artery compliance, cardiac output, or systemic vascular resistance. The findings suggest that hyperglycemia may affect the compliance of the vascular system, resulting in high blood pressure fluctuations.
format	Article
author	Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah
author_facet	Mokhtar, Rafidah Hanim Ayob, Azizi Mohd Noor, Noriah
author_sort	Mokhtar, Rafidah Hanim
title	Blood pressure variability in patients with diabetes mellitus
title_short	Blood pressure variability in patients with diabetes mellitus
title_full	Blood pressure variability in patients with diabetes mellitus
title_fullStr	Blood pressure variability in patients with diabetes mellitus
title_full_unstemmed	Blood pressure variability in patients with diabetes mellitus
title_sort	blood pressure variability in patients with diabetes mellitus
publisher	SAGE Publications
publishDate	2010
url	http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/ http://irep.iium.edu.my/19015/1/blood_pressure_variability_in_patients.pdf
first_indexed	2023-09-18T20:28:20Z
last_indexed	2023-09-18T20:28:20Z
_version_	1777408566954557440

Blood pressure variability in patients with diabetes mellitus

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