The vascular protective effects of polyphenols.

Polyphenols have been proven, both in animal and human studies to be beneficial as vascular protective agents. The effect is claimed to be related to the compound antioxidative properties. This effectively blunts the vasoconstriction process, reported to be due to the excessive generation of reactiv...

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Main Author:	Md. Jaffri, Juliana
Format:	Book Chapter
Language:	English
Published:	IIUM Press 2011
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/18506/ http://irep.iium.edu.my/18506/ http://irep.iium.edu.my/18506/1/CHAPTER_11%5B1%5D.pdf

id	iium-18506
recordtype	eprints
spelling	iium-185062012-08-27T07:57:03Z http://irep.iium.edu.my/18506/ The vascular protective effects of polyphenols. Md. Jaffri, Juliana RS Pharmacy and materia medica Polyphenols have been proven, both in animal and human studies to be beneficial as vascular protective agents. The effect is claimed to be related to the compound antioxidative properties. This effectively blunts the vasoconstriction process, reported to be due to the excessive generation of reactive oxygen species, as observed in many in vitro studies using isolated arteries. The mechanism ofthe vasodilation process invo Ived the endothelium, or it could also be endothelium-independent. In many studies the fornler seemed to be the main pathway. The role of nitric oxide in endothelium-dependent vasodilation activity of the polyphenols is attributed to its protective effect on the soluble gas from deterioration by ROS, as it is capable of neutralizing the radicals. Polyphenols has also been proven to stimulate endothelial nitric oxide synthase to produce more NO, and hence improve vasorelaxation IIUM Press 2011 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/18506/1/CHAPTER_11%5B1%5D.pdf Md. Jaffri, Juliana (2011) The vascular protective effects of polyphenols. In: Current Issues in Pharmacy. IIUM Press, International Islamic University Malaysia, pp. 196-214. ISBN 9789674180195 http://rms.research.iium.edu.my/bookstore/default.aspx
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Md. Jaffri, Juliana The vascular protective effects of polyphenols.
description	Polyphenols have been proven, both in animal and human studies to be beneficial as vascular protective agents. The effect is claimed to be related to the compound antioxidative properties. This effectively blunts the vasoconstriction process, reported to be due to the excessive generation of reactive oxygen species, as observed in many in vitro studies using isolated arteries. The mechanism ofthe vasodilation process invo Ived the endothelium, or it could also be endothelium-independent. In many studies the fornler seemed to be the main pathway. The role of nitric oxide in endothelium-dependent vasodilation activity of the polyphenols is attributed to its protective effect on the soluble gas from deterioration by ROS, as it is capable of neutralizing the radicals. Polyphenols has also been proven to stimulate endothelial nitric oxide synthase to produce more NO, and hence improve vasorelaxation
format	Book Chapter
author	Md. Jaffri, Juliana
author_facet	Md. Jaffri, Juliana
author_sort	Md. Jaffri, Juliana
title	The vascular protective effects of polyphenols.
title_short	The vascular protective effects of polyphenols.
title_full	The vascular protective effects of polyphenols.
title_fullStr	The vascular protective effects of polyphenols.
title_full_unstemmed	The vascular protective effects of polyphenols.
title_sort	vascular protective effects of polyphenols.
publisher	IIUM Press
publishDate	2011
url	http://irep.iium.edu.my/18506/ http://irep.iium.edu.my/18506/ http://irep.iium.edu.my/18506/1/CHAPTER_11%5B1%5D.pdf
first_indexed	2023-09-18T20:27:37Z
last_indexed	2023-09-18T20:27:37Z
_version_	1777408522814750720

The vascular protective effects of polyphenols.

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