Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.

A novel approach to identify compounds possessing adenosine A1 receptor binding activity in the leaves of O. stamineus was developed. O. stamineus extract is one of the components of a functional beverage used in Indonesia for the treatment of kidney stones. In this study, adenosine A1 receptor bind...

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Main Authors:	Sarker, Md. Zaidul Islam, A., Khatib, N.D , Yuliana, J. , Selamat, I., Jaswir, E.G, Wilson, R. , Verpoorte
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2009
Subjects:	TP368 Food processing and manufacture
Online Access:	http://irep.iium.edu.my/18073/ http://irep.iium.edu.my/18073/4/irwandi_10826070903297459.fp.png_v03.pdf

id	iium-18073
recordtype	eprints
spelling	iium-180732016-12-15T07:55:32Z http://irep.iium.edu.my/18073/ Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis. Sarker, Md. Zaidul Islam A., Khatib N.D , Yuliana J. , Selamat I., Jaswir E.G, Wilson R. , Verpoorte TP368 Food processing and manufacture A novel approach to identify compounds possessing adenosine A1 receptor binding activity in the leaves of O. stamineus was developed. O. stamineus extract is one of the components of a functional beverage used in Indonesia for the treatment of kidney stones. In this study, adenosine A1 receptor binding, which is related to the diuretic action in the treatment of kidney stones was tested. A combination of thin layer chromatography of different extracts prepared by extraction with diverse solvents (n-hexane, chloroform, n-butanol and water), and multivariate data analysis based on orthogonal partial least squares proved to be a promising approach to determine these active compounds. Several methoxyflavonoids, fatty acids or terpenoids were estimated to be related to this activity. The results of this study support the traditional use in Indonesia of O. stamineus as a functional drink to treat kidney stones. Taylor & Francis Group 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/18073/4/irwandi_10826070903297459.fp.png_v03.pdf Sarker, Md. Zaidul Islam and A., Khatib and N.D , Yuliana and J. , Selamat and I., Jaswir and E.G, Wilson and R. , Verpoorte (2009) Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis. Journal of Liquid Chromatography & Related Technologies, 32 (19). pp. 2906-2916. ISSN 1082-6076 (p)1520-572X (o)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TP368 Food processing and manufacture
spellingShingle	TP368 Food processing and manufacture Sarker, Md. Zaidul Islam A., Khatib N.D , Yuliana J. , Selamat I., Jaswir E.G, Wilson R. , Verpoorte Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.
description	A novel approach to identify compounds possessing adenosine A1 receptor binding activity in the leaves of O. stamineus was developed. O. stamineus extract is one of the components of a functional beverage used in Indonesia for the treatment of kidney stones. In this study, adenosine A1 receptor binding, which is related to the diuretic action in the treatment of kidney stones was tested. A combination of thin layer chromatography of different extracts prepared by extraction with diverse solvents (n-hexane, chloroform, n-butanol and water), and multivariate data analysis based on orthogonal partial least squares proved to be a promising approach to determine these active compounds. Several methoxyflavonoids, fatty acids or terpenoids were estimated to be related to this activity. The results of this study support the traditional use in Indonesia of O. stamineus as a functional drink to treat kidney stones.
format	Article
author	Sarker, Md. Zaidul Islam A., Khatib N.D , Yuliana J. , Selamat I., Jaswir E.G, Wilson R. , Verpoorte
author_facet	Sarker, Md. Zaidul Islam A., Khatib N.D , Yuliana J. , Selamat I., Jaswir E.G, Wilson R. , Verpoorte
author_sort	Sarker, Md. Zaidul Islam
title	Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.
title_short	Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.
title_full	Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.
title_fullStr	Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.
title_full_unstemmed	Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.
title_sort	identification of possible compounds posessing adenosine a1 receptor binding activity in the leaves of orthosiphon stamineus using tlc and multivariate data analysis.
publisher	Taylor & Francis Group
publishDate	2009
url	http://irep.iium.edu.my/18073/ http://irep.iium.edu.my/18073/4/irwandi_10826070903297459.fp.png_v03.pdf
first_indexed	2023-09-18T20:27:03Z
last_indexed	2023-09-18T20:27:03Z
_version_	1777408486303334400

Identification of possible compounds posessing adenosine A1 receptor binding activity in the leaves of orthosiphon stamineus using TLC and multivariate data analysis.

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