Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration

Pancreatic metastases are very uncommon and originate most commonly from lung, colon, breast and kidney. Ovarian adenocarcinoma has been reported as a primary site of pancreatic metastasis, but diagnosing using EUS-FNA is rarely being reported. Case report We reported a case of multiple metastase...

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Main Authors:	Hasmoni, Mohamed Hadzri, Che Sayuti, Suzila, George, Abraham Matthew, Salleh, Rosemi
Format:	Article
Language:	English
Published:	Blackwell Publishing Asia Pty Ltd 2010
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/17968/ http://irep.iium.edu.my/17968/ http://irep.iium.edu.my/17968/1/Pancreatic_metastases_from_ovarian_carcinoma.pdf

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spelling	iium-179682016-12-15T07:18:48Z http://irep.iium.edu.my/17968/ Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration Hasmoni, Mohamed Hadzri Che Sayuti, Suzila George, Abraham Matthew Salleh, Rosemi R Medicine (General) Pancreatic metastases are very uncommon and originate most commonly from lung, colon, breast and kidney. Ovarian adenocarcinoma has been reported as a primary site of pancreatic metastasis, but diagnosing using EUS-FNA is rarely being reported. Case report We reported a case of multiple metastases to the pancreas from ovarian carcinoma occurred 3 years after original resection of the primary tumour. A 60 year-old lady with prior history of stage IIIC ovarian carcinoma was referred to the Gastroenterology Unit for the evaluation of multiple pancreatic mass. She was diagnosed with the malignancy 3 years earlier and had undergone total abdominal hysterectomy and bilateral salphingo-oophorectomy. She presented with severe epigastric pain associated with nausea and mass per abdomen. She was treated as acute pancreatitis based on clinical and biochemical results. Initial trans-abdominal ultrasound showed multiple pseudocyst within the pancreas, with the largest measuring 4.7 × 3.6 cm. Similar fi ndings were noted from CT scan of the abdomen. EUS revealed multiple cystic lesions with heterogenous appearance at the head and body of the pancreas. Endoscopic ultrasound guided fi ne needle aspiration (EUS-FNA) was performed and the result showed pancreatic papillary adenocarcinoma which was morphologically identical to the surgical specimen of her ovarian mass. She was then treated with palliative chemotherapy. Conclusion EUS-FNA in conjunction with immunohistochemistry is a useful tool for diagnosing pancreatic lesion and mass. Although pancreatic metastases are rare, we still need to exclude the diagnosis for any pancreatic lesion. Blackwell Publishing Asia Pty Ltd 2010 Article PeerReviewed application/pdf en http://irep.iium.edu.my/17968/1/Pancreatic_metastases_from_ovarian_carcinoma.pdf Hasmoni, Mohamed Hadzri and Che Sayuti, Suzila and George, Abraham Matthew and Salleh, Rosemi (2010) Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration. Journal of Gastroenterology and Hepatology, 25 (Supp.2). A48. ISSN 1440-1746 http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1746.2009.06463.x/pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Hasmoni, Mohamed Hadzri Che Sayuti, Suzila George, Abraham Matthew Salleh, Rosemi Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
description	Pancreatic metastases are very uncommon and originate most commonly from lung, colon, breast and kidney. Ovarian adenocarcinoma has been reported as a primary site of pancreatic metastasis, but diagnosing using EUS-FNA is rarely being reported. Case report We reported a case of multiple metastases to the pancreas from ovarian carcinoma occurred 3 years after original resection of the primary tumour. A 60 year-old lady with prior history of stage IIIC ovarian carcinoma was referred to the Gastroenterology Unit for the evaluation of multiple pancreatic mass. She was diagnosed with the malignancy 3 years earlier and had undergone total abdominal hysterectomy and bilateral salphingo-oophorectomy. She presented with severe epigastric pain associated with nausea and mass per abdomen. She was treated as acute pancreatitis based on clinical and biochemical results. Initial trans-abdominal ultrasound showed multiple pseudocyst within the pancreas, with the largest measuring 4.7 × 3.6 cm. Similar fi ndings were noted from CT scan of the abdomen. EUS revealed multiple cystic lesions with heterogenous appearance at the head and body of the pancreas. Endoscopic ultrasound guided fi ne needle aspiration (EUS-FNA) was performed and the result showed pancreatic papillary adenocarcinoma which was morphologically identical to the surgical specimen of her ovarian mass. She was then treated with palliative chemotherapy. Conclusion EUS-FNA in conjunction with immunohistochemistry is a useful tool for diagnosing pancreatic lesion and mass. Although pancreatic metastases are rare, we still need to exclude the diagnosis for any pancreatic lesion.
format	Article
author	Hasmoni, Mohamed Hadzri Che Sayuti, Suzila George, Abraham Matthew Salleh, Rosemi
author_facet	Hasmoni, Mohamed Hadzri Che Sayuti, Suzila George, Abraham Matthew Salleh, Rosemi
author_sort	Hasmoni, Mohamed Hadzri
title	Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
title_short	Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
title_full	Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
title_fullStr	Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
title_full_unstemmed	Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
title_sort	pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration
publisher	Blackwell Publishing Asia Pty Ltd
publishDate	2010
url	http://irep.iium.edu.my/17968/ http://irep.iium.edu.my/17968/ http://irep.iium.edu.my/17968/1/Pancreatic_metastases_from_ovarian_carcinoma.pdf
first_indexed	2023-09-18T20:27:00Z
last_indexed	2023-09-18T20:27:00Z
_version_	1777408483977592832

Pancreatic metastases from ovarian carcinoma—diagnosis by endoscopic ultrasound-guided fine needle aspiration

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