Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria

Aleurites moluccana extracts were found to inhibit the growth of Staphylococcus aureus and Pseudomonas aeruginosa in a previous study.11 The antibacterial activities of acetonitrile, methanol and water extracts of husk, leaf and stem bark of A. moluccana were further investigated against 8 clinical...

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Main Authors:	Abd. Samah, Othman, Mohamad Razar, Rasyidah
Format:	Conference or Workshop Item
Language:	English
Published:	BioTek Journal, India 2009
Subjects:	Q Science (General) R Medicine (General)
Online Access:	http://irep.iium.edu.my/17896/ http://irep.iium.edu.my/17896/1/osman.pdf

id	iium-17896
recordtype	eprints
spelling	iium-178962012-02-03T07:58:02Z http://irep.iium.edu.my/17896/ Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria Abd. Samah, Othman Mohamad Razar, Rasyidah Q Science (General) R Medicine (General) Aleurites moluccana extracts were found to inhibit the growth of Staphylococcus aureus and Pseudomonas aeruginosa in a previous study.11 The antibacterial activities of acetonitrile, methanol and water extracts of husk, leaf and stem bark of A. moluccana were further investigated against 8 clinical isolates. The disc diffusion assays showed that crude extract of A. moluccana inhibited the growth of Staphylococcus aureus (S 277), Streptococcus pyogenes (S 526), Pseudomonas aeruginosa (P 84) and Klebsiella pneumoniae (K 6). The lowest MIC for P. aeruginosa (P 84) was exhibited by methanol extract of stem bark at concentration 98 µg/ml and S. pyogenes (S 526) at 781 µg/ml whilst both S. aureus (S 277) and K. pneumoniae (K 6) exhibited in acetonitrile of husk at 195 µg/ml and 6.25 µg/ml, respectively. The antibacterial action was bactericidal for all bacteria except for S. pyogenes (S 526) where the action was bacteriostatic. The highest polyphenols content was observed in methanol extract of stem bark. The overall results indicate that the extracts from the stem bark are potential source of phytomedicine agents for both Gram-positive and Gram-negative bacteria. BioTek Journal, India 2009-08 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/17896/1/osman.pdf Abd. Samah, Othman and Mohamad Razar, Rasyidah (2009) Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria. In: International Conference on Pharmacy and Advanced Pharmaceutical Sciences, 5-6 October 2009, Yogyakarta, Indonesia. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General) R Medicine (General)
spellingShingle	Q Science (General) R Medicine (General) Abd. Samah, Othman Mohamad Razar, Rasyidah Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
description	Aleurites moluccana extracts were found to inhibit the growth of Staphylococcus aureus and Pseudomonas aeruginosa in a previous study.11 The antibacterial activities of acetonitrile, methanol and water extracts of husk, leaf and stem bark of A. moluccana were further investigated against 8 clinical isolates. The disc diffusion assays showed that crude extract of A. moluccana inhibited the growth of Staphylococcus aureus (S 277), Streptococcus pyogenes (S 526), Pseudomonas aeruginosa (P 84) and Klebsiella pneumoniae (K 6). The lowest MIC for P. aeruginosa (P 84) was exhibited by methanol extract of stem bark at concentration 98 µg/ml and S. pyogenes (S 526) at 781 µg/ml whilst both S. aureus (S 277) and K. pneumoniae (K 6) exhibited in acetonitrile of husk at 195 µg/ml and 6.25 µg/ml, respectively. The antibacterial action was bactericidal for all bacteria except for S. pyogenes (S 526) where the action was bacteriostatic. The highest polyphenols content was observed in methanol extract of stem bark. The overall results indicate that the extracts from the stem bark are potential source of phytomedicine agents for both Gram-positive and Gram-negative bacteria.
format	Conference or Workshop Item
author	Abd. Samah, Othman Mohamad Razar, Rasyidah
author_facet	Abd. Samah, Othman Mohamad Razar, Rasyidah
author_sort	Abd. Samah, Othman
title	Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
title_short	Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
title_full	Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
title_fullStr	Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
title_full_unstemmed	Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
title_sort	antibacterial activity of aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria
publisher	BioTek Journal, India
publishDate	2009
url	http://irep.iium.edu.my/17896/ http://irep.iium.edu.my/17896/1/osman.pdf
first_indexed	2023-09-18T20:26:56Z
last_indexed	2023-09-18T20:26:56Z
_version_	1777408479754977280

Antibacterial activity of Aleurites moluccana against some clinical isolates of gram-positive and gram-negative bacteria

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