Antibacterial and antifungal activities of Cymbopogon nardus essential oil

Essential oils and their components are becoming increasingly popular as naturally occurring antimicrobial agents. In this study the chemical composition and antimicrobial activity of Cymbopogon nardus essential oils were determined. The essential oil components which were identified by GCMS analysi...

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Main Authors: Mohamed Nor, Nurhanani, Abd. Samah, Othman
Format: Article
Language:English
Published: Penerbit USM 2010
Subjects:
Online Access:http://irep.iium.edu.my/17572/
http://irep.iium.edu.my/17572/
http://irep.iium.edu.my/17572/1/antibacterial_and_antifungal_activities_of_cymbopogon_nardus_essential_oil.pdf
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spelling iium-175722012-04-16T23:33:13Z http://irep.iium.edu.my/17572/ Antibacterial and antifungal activities of Cymbopogon nardus essential oil Mohamed Nor, Nurhanani Abd. Samah, Othman QR Microbiology Essential oils and their components are becoming increasingly popular as naturally occurring antimicrobial agents. In this study the chemical composition and antimicrobial activity of Cymbopogon nardus essential oils were determined. The essential oil components which were identified by GCMS analysis are as follows: β-terpinyl acetate, isopulegol, cis-geraniol, citronellyl formate, L-β-pinene, δ-cadinene, γ-elemene and seychellene. The minimum inhibitory concentration (MIC) of essential oils against a few selected pathogenic bacteria (Staphylococcus aureus ATCC 25923, Bacillus anthracis ATCC 14578, Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 35218) and fungi (Candida albicans ATCC 10231 and Cryptococcus neoformans ATCC 90112) were determined using disc diffusion method. The essential oils showed slightly potent inhibitory effects with mean diameter of inhibition zones ranging from 7.5 mm to 9.0 mm. Similar results were also obtained for the fungi, where the essential oils showed inhibitory effects with slightly wider diameter of inhibition zones which ranged from 7.8 mm to 12.0 mm. All microorganisms showed sensitivity towards C. nardus except for P. aeruginosa. The MIC values against these microorganisms ranged from 4.69 mg/mL to 37.5 mg/mL. The findings thus indicate the possibility of exploiting C. nardus essential oil as an effective inhibitor for the growth of some pathogenic microorganisms in the field of medicine. Penerbit USM 2010 Article PeerReviewed application/pdf en http://irep.iium.edu.my/17572/1/antibacterial_and_antifungal_activities_of_cymbopogon_nardus_essential_oil.pdf Mohamed Nor, Nurhanani and Abd. Samah, Othman (2010) Antibacterial and antifungal activities of Cymbopogon nardus essential oil. Malaysian Journal of Pharmaceutical Sciences, 8 (Supp 1). p. 198. ISSN 2180-429X http://web.usm.my/mjps/MJPS%208%20SUPP%201%202010/MJPS%20ART%202%20(145-199).pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QR Microbiology
spellingShingle QR Microbiology
Mohamed Nor, Nurhanani
Abd. Samah, Othman
Antibacterial and antifungal activities of Cymbopogon nardus essential oil
description Essential oils and their components are becoming increasingly popular as naturally occurring antimicrobial agents. In this study the chemical composition and antimicrobial activity of Cymbopogon nardus essential oils were determined. The essential oil components which were identified by GCMS analysis are as follows: β-terpinyl acetate, isopulegol, cis-geraniol, citronellyl formate, L-β-pinene, δ-cadinene, γ-elemene and seychellene. The minimum inhibitory concentration (MIC) of essential oils against a few selected pathogenic bacteria (Staphylococcus aureus ATCC 25923, Bacillus anthracis ATCC 14578, Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 35218) and fungi (Candida albicans ATCC 10231 and Cryptococcus neoformans ATCC 90112) were determined using disc diffusion method. The essential oils showed slightly potent inhibitory effects with mean diameter of inhibition zones ranging from 7.5 mm to 9.0 mm. Similar results were also obtained for the fungi, where the essential oils showed inhibitory effects with slightly wider diameter of inhibition zones which ranged from 7.8 mm to 12.0 mm. All microorganisms showed sensitivity towards C. nardus except for P. aeruginosa. The MIC values against these microorganisms ranged from 4.69 mg/mL to 37.5 mg/mL. The findings thus indicate the possibility of exploiting C. nardus essential oil as an effective inhibitor for the growth of some pathogenic microorganisms in the field of medicine.
format Article
author Mohamed Nor, Nurhanani
Abd. Samah, Othman
author_facet Mohamed Nor, Nurhanani
Abd. Samah, Othman
author_sort Mohamed Nor, Nurhanani
title Antibacterial and antifungal activities of Cymbopogon nardus essential oil
title_short Antibacterial and antifungal activities of Cymbopogon nardus essential oil
title_full Antibacterial and antifungal activities of Cymbopogon nardus essential oil
title_fullStr Antibacterial and antifungal activities of Cymbopogon nardus essential oil
title_full_unstemmed Antibacterial and antifungal activities of Cymbopogon nardus essential oil
title_sort antibacterial and antifungal activities of cymbopogon nardus essential oil
publisher Penerbit USM
publishDate 2010
url http://irep.iium.edu.my/17572/
http://irep.iium.edu.my/17572/
http://irep.iium.edu.my/17572/1/antibacterial_and_antifungal_activities_of_cymbopogon_nardus_essential_oil.pdf
first_indexed 2023-09-18T20:26:30Z
last_indexed 2023-09-18T20:26:30Z
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