Synthesis and structural studies of 2-[3-(4-methoxybenzoyl) thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl) propionic acid
Two 4-methoxybenzoylthiourea of propionic acid namely 2-[3-(4- Two 4-methoxybenzoylthiourea of propionic acid namely 2-[3-(4-methoxybenzoyl)thioureido]phenylpropionic acid (I) and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl)propionic acid (II) have been successfully synthesized. The compo...
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| Language: | English |
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2010
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| Online Access: | http://irep.iium.edu.my/15868/ http://irep.iium.edu.my/15868/ http://irep.iium.edu.my/15868/1/2010_IRIIE_Kamarul_et_al_Aromatic.pdf |
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iium-158682012-01-30T06:17:39Z http://irep.iium.edu.my/15868/ Synthesis and structural studies of 2-[3-(4-methoxybenzoyl) thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl) propionic acid Ngah, Nurziana M Yamin, Bohari Kassim, Mohammad QD Chemistry Two 4-methoxybenzoylthiourea of propionic acid namely 2-[3-(4- Two 4-methoxybenzoylthiourea of propionic acid namely 2-[3-(4-methoxybenzoyl)thioureido]phenylpropionic acid (I) and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl)propionic acid (II) have been successfully synthesized. The compounds were analyzed and characterized by elemental analysis, infrared spectroscopy and X-ray crystallography. Both compounds crystallized in orthorhombic crystal system with space group P21 21 21, a = 5.0364(13) Å, b = 16.716(4) Å, c = 23.040(6) Å and Z = 4 and Pbcn, a = 18.247(4) Å, b = 14.083(3) Å, c = 14.736(3) Å and Z = 8, respectively. As in most carbonoylthiourea compounds, the molecules adopts trans-cis configuration with respect to the position of 4-methoxybenzoyl and the propionic acid moieties against the thiono S atom across their C-N bonds. Molecule (I) is associated with one methanol molecule as molecule of recrystalization. 2010 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/15868/1/2010_IRIIE_Kamarul_et_al_Aromatic.pdf Ngah, Nurziana and M Yamin, Bohari and Kassim, Mohammad (2010) Synthesis and structural studies of 2-[3-(4-methoxybenzoyl) thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl) propionic acid. In: IIUM Research, Innovation & Invention Exhibition (IRIIE 2010), 26 - 27 January 2010, Kuala Lumpur. http://www.iium.edu.my/irie/10/info/Programme_Book%20Part_2.pdf |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
QD Chemistry |
| spellingShingle |
QD Chemistry Ngah, Nurziana M Yamin, Bohari Kassim, Mohammad Synthesis and structural studies of 2-[3-(4-methoxybenzoyl) thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl) propionic acid |
| description |
Two 4-methoxybenzoylthiourea of propionic acid namely 2-[3-(4- Two 4-methoxybenzoylthiourea of propionic acid namely 2-[3-(4-methoxybenzoyl)thioureido]phenylpropionic acid (I) and 2-[3-(4-methoxybenzoyl) thioureido]-3-(1H-indole-3-yl)propionic acid (II) have been successfully synthesized.
The compounds were analyzed and characterized by elemental analysis, infrared spectroscopy and X-ray crystallography. Both compounds crystallized in orthorhombic crystal system with space group P21 21 21, a = 5.0364(13) Å, b = 16.716(4) Å, c = 23.040(6) Å and Z = 4 and Pbcn, a = 18.247(4) Å, b = 14.083(3) Å, c = 14.736(3) Å and Z = 8, respectively. As in most carbonoylthiourea compounds, the molecules adopts
trans-cis configuration with respect to the position of 4-methoxybenzoyl and the propionic acid moieties against the thiono S atom across their C-N bonds. Molecule (I) is associated with one methanol molecule as molecule of recrystalization. |
| format |
Conference or Workshop Item |
| author |
Ngah, Nurziana M Yamin, Bohari Kassim, Mohammad |
| author_facet |
Ngah, Nurziana M Yamin, Bohari Kassim, Mohammad |
| author_sort |
Ngah, Nurziana |
| title |
Synthesis and structural studies of 2-[3-(4-methoxybenzoyl)
thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl)
thioureido]-3-(1H-indole-3-yl) propionic acid |
| title_short |
Synthesis and structural studies of 2-[3-(4-methoxybenzoyl)
thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl)
thioureido]-3-(1H-indole-3-yl) propionic acid |
| title_full |
Synthesis and structural studies of 2-[3-(4-methoxybenzoyl)
thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl)
thioureido]-3-(1H-indole-3-yl) propionic acid |
| title_fullStr |
Synthesis and structural studies of 2-[3-(4-methoxybenzoyl)
thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl)
thioureido]-3-(1H-indole-3-yl) propionic acid |
| title_full_unstemmed |
Synthesis and structural studies of 2-[3-(4-methoxybenzoyl)
thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl)
thioureido]-3-(1H-indole-3-yl) propionic acid |
| title_sort |
synthesis and structural studies of 2-[3-(4-methoxybenzoyl)
thioureido]phenyl propionic acid and 2-[3-(4-methoxybenzoyl)
thioureido]-3-(1h-indole-3-yl) propionic acid |
| publishDate |
2010 |
| url |
http://irep.iium.edu.my/15868/ http://irep.iium.edu.my/15868/ http://irep.iium.edu.my/15868/1/2010_IRIIE_Kamarul_et_al_Aromatic.pdf |
| first_indexed |
2023-09-18T20:24:46Z |
| last_indexed |
2023-09-18T20:24:46Z |
| _version_ |
1777408343148593152 |