Potential beta-glucosidase inhibitor from Malaysian medical plants
Diabetes is one of the chronic diseases affecting worldwide population. Presently, there is a growing interest in herbal remedies due to the side effects associated with the use of insulin and oral hypoglycaemic agents for diabetic patient. Therefore an investigation is required in a bionetwork ric...
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2009
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| Online Access: | http://irep.iium.edu.my/13894/ http://irep.iium.edu.my/13894/ http://irep.iium.edu.my/13894/1/MICOTRIBE_2009_204-211.pdf |
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eprints |
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iium-138942012-01-14T00:33:43Z http://irep.iium.edu.my/13894/ Potential beta-glucosidase inhibitor from Malaysian medical plants Ahmad Barkat, Anumsima Jamal, Parveen Amid, Azura R Medicine (General) TP248.13 Biotechnology Diabetes is one of the chronic diseases affecting worldwide population. Presently, there is a growing interest in herbal remedies due to the side effects associated with the use of insulin and oral hypoglycaemic agents for diabetic patient. Therefore an investigation is required in a bionetwork rich and industrially-developed country like Malaysia to use alternative approaches to treat diabetics, such as plant based medicine. In this study, forty types of Malaysian antidiabetic plants were examined on the basis of their uses in traditional medicines throughout Southeast Asia, to develop an understanding of the distribution and to give an assessment of the diversity present in the selected plants. Extracts of all 40 species of Malaysian medicinal plants were examined for �-glucosidase inhibition using an in-vitro model. Most of the plants showed varying degree of inhibitory activity (%) but Centella asiatica had the maximum percentage of �-glucosidase inhibitory activity (99.03%) while the second best is Morinda citrifolia with 96.37% inhibitory activity. Another two potential plants which gave higher inhibitory activity were Cucumis sativus (93.95%) and Euphorbia tircalli L. (90.56%). These potential plants with �-glucosidase inhibitory activity can be a hope for millions for treatment of diabetes and will also help in reducing the dependence on synthetic drugs in the future. 2009-12 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/13894/1/MICOTRIBE_2009_204-211.pdf Ahmad Barkat, Anumsima and Jamal, Parveen and Amid, Azura (2009) Potential beta-glucosidase inhibitor from Malaysian medical plants. In: Malaysian International Conference on Trends in Bioprocess Engineering (MICOTriBE 2009), 12-13 December 2009, PWTC, Kuala Lumpur. http://publicweb.unimap.edu.my/~MICOTriBE2009/ |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
R Medicine (General) TP248.13 Biotechnology |
| spellingShingle |
R Medicine (General) TP248.13 Biotechnology Ahmad Barkat, Anumsima Jamal, Parveen Amid, Azura Potential beta-glucosidase inhibitor from Malaysian medical plants |
| description |
Diabetes is one of the chronic diseases affecting worldwide population. Presently, there is a growing interest in herbal remedies due to the side effects associated with the
use of insulin and oral hypoglycaemic agents for diabetic patient. Therefore an investigation is required in a bionetwork rich and industrially-developed country like
Malaysia to use alternative approaches to treat diabetics, such as plant based medicine. In this study, forty types of Malaysian antidiabetic plants were examined on the basis
of their uses in traditional medicines throughout Southeast Asia, to develop an understanding of the distribution and to give an assessment of the diversity present in
the selected plants. Extracts of all 40 species of Malaysian medicinal plants were examined for �-glucosidase inhibition using an in-vitro model. Most of the plants
showed varying degree of inhibitory activity (%) but Centella asiatica had the maximum percentage of �-glucosidase inhibitory activity (99.03%) while the second
best is Morinda citrifolia with 96.37% inhibitory activity. Another two potential plants which gave higher inhibitory activity were Cucumis sativus (93.95%) and Euphorbia
tircalli L. (90.56%). These potential plants with �-glucosidase inhibitory activity can be a hope for millions for treatment of diabetes and will also help in reducing the
dependence on synthetic drugs in the future. |
| format |
Conference or Workshop Item |
| author |
Ahmad Barkat, Anumsima Jamal, Parveen Amid, Azura |
| author_facet |
Ahmad Barkat, Anumsima Jamal, Parveen Amid, Azura |
| author_sort |
Ahmad Barkat, Anumsima |
| title |
Potential beta-glucosidase inhibitor from Malaysian medical plants |
| title_short |
Potential beta-glucosidase inhibitor from Malaysian medical plants |
| title_full |
Potential beta-glucosidase inhibitor from Malaysian medical plants |
| title_fullStr |
Potential beta-glucosidase inhibitor from Malaysian medical plants |
| title_full_unstemmed |
Potential beta-glucosidase inhibitor from Malaysian medical plants |
| title_sort |
potential beta-glucosidase inhibitor from malaysian medical plants |
| publishDate |
2009 |
| url |
http://irep.iium.edu.my/13894/ http://irep.iium.edu.my/13894/ http://irep.iium.edu.my/13894/1/MICOTRIBE_2009_204-211.pdf |
| first_indexed |
2023-09-18T20:23:04Z |
| last_indexed |
2023-09-18T20:23:04Z |
| _version_ |
1777408235735613440 |