Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study

Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study

Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The ai...

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Main Authors: Myint, Yi Yi, Tun, Ye
Format: Conference or Workshop Item
Language:English
Published: 2011
Subjects:
QM Human anatomy
Online Access:http://irep.iium.edu.my/13252/
http://irep.iium.edu.my/13252/
http://irep.iium.edu.my/13252/1/oral_presentation_2011.pdf
id iium-13252
recordtype eprints
spelling iium-132522017-06-21T06:24:09Z http://irep.iium.edu.my/13252/ Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study Myint, Yi Yi Tun, Ye QM Human anatomy Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore cellular attachments in most superficial esophageal cells of non- erosive (NERD) patients. The study group included 8 (NERD) patients and 5 normal controls. Specimens were routinely processed for SEM. The nature of cellular attachment and intercellular spaces between superficial cells of esophageal mucosa were viewed by SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings supported the concept of abnormal tissue resistance in pathogenesis of NERD patients. Key words: Non-erosive Reflux Disease (NERD), Dilatation Intercellular spaces (DIS), scanning electron microscopy (SEM) 2011-12-21 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/13252/1/oral_presentation_2011.pdf Myint, Yi Yi and Tun, Ye (2011) Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study. In: 20th Scientific Conference of Microscopy Society of Malaysia , 20th to 22nd December 2011, Permaisuri resort, Port Dickson. (Unpublished) http://online.nuclearmalaysia.gov.my/sems/emsm2011/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QM Human anatomy
spellingShingle QM Human anatomy
Myint, Yi Yi
Tun, Ye
Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
description Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore cellular attachments in most superficial esophageal cells of non- erosive (NERD) patients. The study group included 8 (NERD) patients and 5 normal controls. Specimens were routinely processed for SEM. The nature of cellular attachment and intercellular spaces between superficial cells of esophageal mucosa were viewed by SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings supported the concept of abnormal tissue resistance in pathogenesis of NERD patients. Key words: Non-erosive Reflux Disease (NERD), Dilatation Intercellular spaces (DIS), scanning electron microscopy (SEM)
format Conference or Workshop Item
author Myint, Yi Yi
Tun, Ye
author_facet Myint, Yi Yi
Tun, Ye
author_sort Myint, Yi Yi
title Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
title_short Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
title_full Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
title_fullStr Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
title_full_unstemmed Esophageal surface cells in Non-erosive Reflux Disease (NERD): Scanning electron microscopic study
title_sort esophageal surface cells in non-erosive reflux disease (nerd): scanning electron microscopic study
publishDate 2011
url http://irep.iium.edu.my/13252/
http://irep.iium.edu.my/13252/
http://irep.iium.edu.my/13252/1/oral_presentation_2011.pdf
first_indexed 2023-09-18T20:22:26Z
last_indexed 2023-09-18T20:22:26Z
_version_ 1777408196286087168

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