Primary plasma cell leukemia presented as progressive paraplegia: a case report

Plasma cell leukemia (PCL) is a rare plasma cell disorder. It is the leukemic variant of multiple myeloma. A 52-year-old man with an atypical presentation of primary plasma cell leukemia is reported. The patient presented with paraparesis which progressively worsened to paraplegia. MRI of the spine...

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Main Authors:	Hasmoni, Mohamed Hadzri, Abdul Wahid, Fadilah, Cheong, Soon Keng
Format:	Article
Language:	English
Published:	Southern Medical Association 2009
Subjects:	RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/12330/ http://irep.iium.edu.my/12330/ http://irep.iium.edu.my/12330/ http://irep.iium.edu.my/12330/1/Primary_Plasma_Cell_Leukemia_Presented_as.33%5B1%5D.pdf

id	iium-12330
recordtype	eprints
spelling	iium-123302011-12-27T23:06:44Z http://irep.iium.edu.my/12330/ Primary plasma cell leukemia presented as progressive paraplegia: a case report Hasmoni, Mohamed Hadzri Abdul Wahid, Fadilah Cheong, Soon Keng RC0254 Neoplasms. Tumors. Oncology (including Cancer) Plasma cell leukemia (PCL) is a rare plasma cell disorder. It is the leukemic variant of multiple myeloma. A 52-year-old man with an atypical presentation of primary plasma cell leukemia is reported. The patient presented with paraparesis which progressively worsened to paraplegia. MRI of the spine showed an extradural mass causing cord compression and multiple bony erosions from soft tissue masses. Peripheral blood film examination and bone marrow aspiration showed numerous plasmablasts. Atypical cells expressed surface and cytoplasmic lambda light chain on immunochemical studies, surface CD45 and CD38. To our knowledge, primary PCL presenting with progressive paraplegia has not been reported in the literature. Southern Medical Association 2009-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/12330/1/Primary_Plasma_Cell_Leukemia_Presented_as.33%5B1%5D.pdf Hasmoni, Mohamed Hadzri and Abdul Wahid, Fadilah and Cheong, Soon Keng (2009) Primary plasma cell leukemia presented as progressive paraplegia: a case report. Southern Medical Journal, 102 (1). pp. 101-103. ISSN 0038-4348 (P), 1541-8243 (O) http://journals.lww.com/smajournalonline/Fulltext/2009/01000/Primary_Plasma_Cell_Leukemia_Presented_as.33.aspx# 10.1097/SMJ.0b013e31818018c1
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC0254 Neoplasms. Tumors. Oncology (including Cancer)
spellingShingle	RC0254 Neoplasms. Tumors. Oncology (including Cancer) Hasmoni, Mohamed Hadzri Abdul Wahid, Fadilah Cheong, Soon Keng Primary plasma cell leukemia presented as progressive paraplegia: a case report
description	Plasma cell leukemia (PCL) is a rare plasma cell disorder. It is the leukemic variant of multiple myeloma. A 52-year-old man with an atypical presentation of primary plasma cell leukemia is reported. The patient presented with paraparesis which progressively worsened to paraplegia. MRI of the spine showed an extradural mass causing cord compression and multiple bony erosions from soft tissue masses. Peripheral blood film examination and bone marrow aspiration showed numerous plasmablasts. Atypical cells expressed surface and cytoplasmic lambda light chain on immunochemical studies, surface CD45 and CD38. To our knowledge, primary PCL presenting with progressive paraplegia has not been reported in the literature.
format	Article
author	Hasmoni, Mohamed Hadzri Abdul Wahid, Fadilah Cheong, Soon Keng
author_facet	Hasmoni, Mohamed Hadzri Abdul Wahid, Fadilah Cheong, Soon Keng
author_sort	Hasmoni, Mohamed Hadzri
title	Primary plasma cell leukemia presented as progressive paraplegia: a case report
title_short	Primary plasma cell leukemia presented as progressive paraplegia: a case report
title_full	Primary plasma cell leukemia presented as progressive paraplegia: a case report
title_fullStr	Primary plasma cell leukemia presented as progressive paraplegia: a case report
title_full_unstemmed	Primary plasma cell leukemia presented as progressive paraplegia: a case report
title_sort	primary plasma cell leukemia presented as progressive paraplegia: a case report
publisher	Southern Medical Association
publishDate	2009
url	http://irep.iium.edu.my/12330/ http://irep.iium.edu.my/12330/ http://irep.iium.edu.my/12330/ http://irep.iium.edu.my/12330/1/Primary_Plasma_Cell_Leukemia_Presented_as.33%5B1%5D.pdf
first_indexed	2023-09-18T20:21:32Z
last_indexed	2023-09-18T20:21:32Z
_version_	1777408140034179072

Primary plasma cell leukemia presented as progressive paraplegia: a case report

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