Study of cytotoxic activities of Rubraxanthone
Rubraxanthone is a prenylated xanthone that was isolated from Garcinia euginifolia (Guttiferae). It is having antimicrobial and antiplatelet activating factor activities. The research is aimed to study a cytotoxic activity of the compound by using in vitro cell culture technique. In order to evaluat...
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2009
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| Online Access: | http://irep.iium.edu.my/12122/ http://irep.iium.edu.my/12122/ http://irep.iium.edu.my/12122/1/ICMC-Bandung-1.pdf http://irep.iium.edu.my/12122/2/bandungcover.pdf |
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iium-12122 |
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eprints |
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iium-121222014-12-09T01:42:19Z http://irep.iium.edu.my/12122/ Study of cytotoxic activities of Rubraxanthone Bakhtiar, M. Taher Sawaneh, Fatoumata Darnis, Deny Susanti Q Science (General) Rubraxanthone is a prenylated xanthone that was isolated from Garcinia euginifolia (Guttiferae). It is having antimicrobial and antiplatelet activating factor activities. The research is aimed to study a cytotoxic activity of the compound by using in vitro cell culture technique. In order to evaluate the activity against cancer, the compound is exposed for its activity against several cancerous cell lines. It is tested against breast (MCF-7), bone (Saos-2), cervix (SiHa and C33A), colorectal (HCT-116), esophageal (TE1 and TE2), rectum (SW837) cancer cells and normal fibroblast (NHDF). The cells were seeded in a 96-well plate a density of 2 x 10^5 cells/mL. The compound is being tested to confluent celss for two days. Antiproliverative activity is evaluated by 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazoliumbromide) (MTT) assay. It is found that the compound exhibits a moderate activity against all type of the cells. 2009-08-06 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/12122/1/ICMC-Bandung-1.pdf application/pdf en http://irep.iium.edu.my/12122/2/bandungcover.pdf Bakhtiar, M. Taher and Sawaneh, Fatoumata and Darnis, Deny Susanti (2009) Study of cytotoxic activities of Rubraxanthone. In: Bandung International Conference on Medicinal Chemistry, 6-8 August 2009, Bandung, Indonesia. http://www.icmc2009.fa.itb.ac.id/ |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English |
| topic |
Q Science (General) |
| spellingShingle |
Q Science (General) Bakhtiar, M. Taher Sawaneh, Fatoumata Darnis, Deny Susanti Study of cytotoxic activities of Rubraxanthone |
| description |
Rubraxanthone is a prenylated xanthone that was isolated from Garcinia euginifolia (Guttiferae). It is having antimicrobial and antiplatelet activating factor activities. The research is aimed to study a cytotoxic activity of the compound by using in vitro cell culture technique. In order to evaluate the activity against cancer, the compound is exposed for its activity against several cancerous cell lines. It is tested against breast (MCF-7), bone (Saos-2), cervix (SiHa and C33A), colorectal (HCT-116), esophageal (TE1 and TE2), rectum (SW837) cancer cells and normal fibroblast (NHDF). The cells were seeded in a 96-well plate a density of 2 x 10^5 cells/mL. The compound is being tested to confluent celss for two days. Antiproliverative activity is evaluated by 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazoliumbromide) (MTT) assay. It is found that the compound exhibits a moderate activity against all type of the cells. |
| format |
Conference or Workshop Item |
| author |
Bakhtiar, M. Taher Sawaneh, Fatoumata Darnis, Deny Susanti |
| author_facet |
Bakhtiar, M. Taher Sawaneh, Fatoumata Darnis, Deny Susanti |
| author_sort |
Bakhtiar, M. Taher |
| title |
Study of cytotoxic activities of Rubraxanthone |
| title_short |
Study of cytotoxic activities of Rubraxanthone |
| title_full |
Study of cytotoxic activities of Rubraxanthone |
| title_fullStr |
Study of cytotoxic activities of Rubraxanthone |
| title_full_unstemmed |
Study of cytotoxic activities of Rubraxanthone |
| title_sort |
study of cytotoxic activities of rubraxanthone |
| publishDate |
2009 |
| url |
http://irep.iium.edu.my/12122/ http://irep.iium.edu.my/12122/ http://irep.iium.edu.my/12122/1/ICMC-Bandung-1.pdf http://irep.iium.edu.my/12122/2/bandungcover.pdf |
| first_indexed |
2023-09-18T20:21:21Z |
| last_indexed |
2023-09-18T20:21:21Z |
| _version_ |
1777408128306905088 |