The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles

The prevalence of diabetes in Malaysia within 10 years had doubled (Public Health Institute, 2008). The complication of the disease has more impact and burden on the health (ADA, 2008). The seriousness and the occurrence of the complications are closely related with tightly control hyperglycaemia (U...

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Main Authors:	Kasmuri, Abdul Razak, Mohd. Hassan, Norazian, Arifin, Syamsul, Mehat, Isa, Mat Taib, Nurhaya
Format:	Conference or Workshop Item
Language:	English
Published:	2010
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/11407/ http://irep.iium.edu.my/11407/1/POSTERmspp2010.ppt

id	iium-11407
recordtype	eprints
spelling	iium-114072011-12-19T09:43:37Z http://irep.iium.edu.my/11407/ The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles Kasmuri, Abdul Razak Mohd. Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya RM Therapeutics. Pharmacology The prevalence of diabetes in Malaysia within 10 years had doubled (Public Health Institute, 2008). The complication of the disease has more impact and burden on the health (ADA, 2008). The seriousness and the occurrence of the complications are closely related with tightly control hyperglycaemia (UKPDS,1998). Thus it is a better approach to screen substance that able to prevent postprandial hyperglycaemia that can cause fluctuating glucose levels i.e. to screen substance that able to decrease glucose absorption in GIT. Pithecellobium jiringa is already known to have antidiabetic property among Malaysians and used as its traditional remedy (Mohamed et al., 2005). A preliminary study showed that the plant has hypoglycaemic effect (Thevathasan, 1972). Radhiah et al. (2004) and Tungsarikarn et al. (2008) found that the plant has glucose lowering effect and the latter also proved the plant extract has an effect on alpha-glucosidase enzyme. On the other hand the seeds containing djenkolic acid which can cause djenkolism, which is a toxicity effect characterized by acute renal failure, urinary obstruction and spasmodic pain (Barceloux, 2009). The study was conducted with the aim at elaborating and reconciling the previous finding on the glucose lowering effect of P. jiringa. In order to make it more explorative, both of the seed and pericarp extracts of the plant were studied. 2010-06 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/11407/1/POSTERmspp2010.ppt Kasmuri, Abdul Razak and Mohd. Hassan, Norazian and Arifin, Syamsul and Mehat, Isa and Mat Taib, Nurhaya (2010) The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles. In: Malaysian Society of Pharmacology and Physiology.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Kasmuri, Abdul Razak Mohd. Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
description	The prevalence of diabetes in Malaysia within 10 years had doubled (Public Health Institute, 2008). The complication of the disease has more impact and burden on the health (ADA, 2008). The seriousness and the occurrence of the complications are closely related with tightly control hyperglycaemia (UKPDS,1998). Thus it is a better approach to screen substance that able to prevent postprandial hyperglycaemia that can cause fluctuating glucose levels i.e. to screen substance that able to decrease glucose absorption in GIT. Pithecellobium jiringa is already known to have antidiabetic property among Malaysians and used as its traditional remedy (Mohamed et al., 2005). A preliminary study showed that the plant has hypoglycaemic effect (Thevathasan, 1972). Radhiah et al. (2004) and Tungsarikarn et al. (2008) found that the plant has glucose lowering effect and the latter also proved the plant extract has an effect on alpha-glucosidase enzyme. On the other hand the seeds containing djenkolic acid which can cause djenkolism, which is a toxicity effect characterized by acute renal failure, urinary obstruction and spasmodic pain (Barceloux, 2009). The study was conducted with the aim at elaborating and reconciling the previous finding on the glucose lowering effect of P. jiringa. In order to make it more explorative, both of the seed and pericarp extracts of the plant were studied.
format	Conference or Workshop Item
author	Kasmuri, Abdul Razak Mohd. Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya
author_facet	Kasmuri, Abdul Razak Mohd. Hassan, Norazian Arifin, Syamsul Mehat, Isa Mat Taib, Nurhaya
author_sort	Kasmuri, Abdul Razak
title	The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
title_short	The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
title_full	The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
title_fullStr	The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
title_full_unstemmed	The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
title_sort	inhibition of glucose absorption of seed and pericarp extracts of pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles
publishDate	2010
url	http://irep.iium.edu.my/11407/ http://irep.iium.edu.my/11407/1/POSTERmspp2010.ppt
first_indexed	2023-09-18T20:20:44Z
last_indexed	2023-09-18T20:20:44Z
_version_	1777408089011519488

The inhibition of glucose absorption of seed and pericarp extracts of Pithecellobium jiringa on intestinal tissues preparation and their phytochemical profiles

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