Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion

In many clinical disciplines used of bone graft is unavoidable such as to replace bone loss due to trauma, to fill in bone defect after tumour excision, for reconstructive surgery or spinal fusion. Calcium phosphate based hydroxyapatite is widely used bone graft substitute due to its similarity with...

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Main Authors:	Buyong, Zunariah, Zakaria@Mohamad, Zamzuri, Khalid, Kamarul Ariffin, Zulkifly, Ahmad Hafiz, Abdel Wahab, Emad Mohamad Nafie, Ab Rahman, Jamalludin, Abdul Rashid, Mohd Amran
Format:	Conference or Workshop Item
Language:	English English
Published:	2012
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/11275/ http://irep.iium.edu.my/11275/ http://irep.iium.edu.my/11275/7/Poster%20iCONT2012%20Zunariah.pdf http://irep.iium.edu.my/11275/13/ICONT%202012%20BOOK%20OF%20ABSTRACT.pdf

id	iium-11275
recordtype	eprints
spelling	iium-112752019-01-23T08:45:15Z http://irep.iium.edu.my/11275/ Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion Buyong, Zunariah Zakaria@Mohamad, Zamzuri Khalid, Kamarul Ariffin Zulkifly, Ahmad Hafiz Abdel Wahab, Emad Mohamad Nafie Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran R Medicine (General) In many clinical disciplines used of bone graft is unavoidable such as to replace bone loss due to trauma, to fill in bone defect after tumour excision, for reconstructive surgery or spinal fusion. Calcium phosphate based hydroxyapatite is widely used bone graft substitute due to its similarity with the mineral components of bone matrix. This study was conducted to evaluate bone formation effect of this biomaterial in posterolateral intertransverse lumbar fusion, a novel site for its application. Twelve adult New Zealand white rabbits underwent bilateral intertransverse lumbar spinal fusion at L5-L6 vertebrae. One site of the animals was implanted with hydroxyapatite granules (HA group) while the contralateral sides received autograft and served as the control (AUTO group). Bone formation was assessed at 6 and 16 weeks by undecalcified histology and scanning electron microscopy. New bone was formed on the surface of hydroxyapatite granules and continually formed even at 16 weeks. Close contact between new bone and hydroxyapatite granules was demonstrated by scanning electron microscopy. 2012-05-30 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/11275/7/Poster%20iCONT2012%20Zunariah.pdf application/pdf en http://irep.iium.edu.my/11275/13/ICONT%202012%20BOOK%20OF%20ABSTRACT.pdf Buyong, Zunariah and Zakaria@Mohamad, Zamzuri and Khalid, Kamarul Ariffin and Zulkifly, Ahmad Hafiz and Abdel Wahab, Emad Mohamad Nafie and Ab Rahman, Jamalludin and Abdul Rashid, Mohd Amran (2012) Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion. In: International Conference on Nanotechnology, ICONT 2012, 30 May – 01 June 2012, MS garden Hotel, Kuantan, Pahang. (Unpublished) http://umpir.ump.edu.my/id/eprint/10564/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Buyong, Zunariah Zakaria@Mohamad, Zamzuri Khalid, Kamarul Ariffin Zulkifly, Ahmad Hafiz Abdel Wahab, Emad Mohamad Nafie Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
description	In many clinical disciplines used of bone graft is unavoidable such as to replace bone loss due to trauma, to fill in bone defect after tumour excision, for reconstructive surgery or spinal fusion. Calcium phosphate based hydroxyapatite is widely used bone graft substitute due to its similarity with the mineral components of bone matrix. This study was conducted to evaluate bone formation effect of this biomaterial in posterolateral intertransverse lumbar fusion, a novel site for its application. Twelve adult New Zealand white rabbits underwent bilateral intertransverse lumbar spinal fusion at L5-L6 vertebrae. One site of the animals was implanted with hydroxyapatite granules (HA group) while the contralateral sides received autograft and served as the control (AUTO group). Bone formation was assessed at 6 and 16 weeks by undecalcified histology and scanning electron microscopy. New bone was formed on the surface of hydroxyapatite granules and continually formed even at 16 weeks. Close contact between new bone and hydroxyapatite granules was demonstrated by scanning electron microscopy.
format	Conference or Workshop Item
author	Buyong, Zunariah Zakaria@Mohamad, Zamzuri Khalid, Kamarul Ariffin Zulkifly, Ahmad Hafiz Abdel Wahab, Emad Mohamad Nafie Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran
author_facet	Buyong, Zunariah Zakaria@Mohamad, Zamzuri Khalid, Kamarul Ariffin Zulkifly, Ahmad Hafiz Abdel Wahab, Emad Mohamad Nafie Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran
author_sort	Buyong, Zunariah
title	Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
title_short	Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
title_full	Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
title_fullStr	Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
title_full_unstemmed	Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
title_sort	application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion
publishDate	2012
url	http://irep.iium.edu.my/11275/ http://irep.iium.edu.my/11275/ http://irep.iium.edu.my/11275/7/Poster%20iCONT2012%20Zunariah.pdf http://irep.iium.edu.my/11275/13/ICONT%202012%20BOOK%20OF%20ABSTRACT.pdf
first_indexed	2023-09-18T20:20:36Z
last_indexed	2023-09-18T20:20:36Z
_version_	1777408081378934784

Application of hydroxyapatite granules in posterolateral intertransverse lumbar spinal fusion

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