Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan

A retrospective study was conducted to investigate 183 serologically-confirmed cases of dengue fever (DF) admitted from October 2004 to March 2005 in a large hospital in Pahang. Clinical and laboratory features, progress and outcome of these patients were analysed in order to identify risk factors a...

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Main Authors:	Tee, H. P., How, Soon Hin, Ab Rahman, Jamalludin, Mohamad Nor, Fariz Safhan, M., Mohd Sapian, Kuan, Yeh Chunn, S., Sapari
Format:	Article
Language:	English
Published:	Malaysian Medical Associations 2009
Subjects:	R Medicine (General) RA Public aspects of medicine
Online Access:	http://irep.iium.edu.my/1126/ http://irep.iium.edu.my/1126/ http://irep.iium.edu.my/1126/1/Risk_Factors_Associated_with_Development_of_Dengue.pdf

id	iium-1126
recordtype	eprints
spelling	iium-11262016-03-10T03:59:46Z http://irep.iium.edu.my/1126/ Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan Tee, H. P. How, Soon Hin Ab Rahman, Jamalludin Mohamad Nor, Fariz Safhan M., Mohd Sapian Kuan, Yeh Chunn S., Sapari R Medicine (General) RA Public aspects of medicine A retrospective study was conducted to investigate 183 serologically-confirmed cases of dengue fever (DF) admitted from October 2004 to March 2005 in a large hospital in Pahang. Clinical and laboratory features, progress and outcome of these patients were analysed in order to identify risk factors associated with development of dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). Individually, we found that older patients, secondary dengue infection, high baseline haematocrit levels, low platelet levels and prolonged activated partial thromboplastin time (APTT) ratio were significant associations with bleeding tendencies. Of these risk factors, haematocrit and APTT ratio were two independent significant risk factors on multivariate analysis. Older patients with primary infection and younger patients with secondary infection had significant bleeding tendencies. We also verified the validity of the haematocrit levels suggested as cut-off levels for plasma leakage for the Malaysian population by Malaysian Clinical Practice Guidelines for Dengue Infection in Adults (2003). Malaysian Medical Associations 2009-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/1126/1/Risk_Factors_Associated_with_Development_of_Dengue.pdf Tee, H. P. and How, Soon Hin and Ab Rahman, Jamalludin and Mohamad Nor, Fariz Safhan and M., Mohd Sapian and Kuan, Yeh Chunn and S., Sapari (2009) Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan. Medical Journal of Malaysia, 64 (4). pp. 263-267. ISSN 0300-5283 http://www.e-mjm.org/2009/v64n4/index.html
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RA Public aspects of medicine
spellingShingle	R Medicine (General) RA Public aspects of medicine Tee, H. P. How, Soon Hin Ab Rahman, Jamalludin Mohamad Nor, Fariz Safhan M., Mohd Sapian Kuan, Yeh Chunn S., Sapari Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan
description	A retrospective study was conducted to investigate 183 serologically-confirmed cases of dengue fever (DF) admitted from October 2004 to March 2005 in a large hospital in Pahang. Clinical and laboratory features, progress and outcome of these patients were analysed in order to identify risk factors associated with development of dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). Individually, we found that older patients, secondary dengue infection, high baseline haematocrit levels, low platelet levels and prolonged activated partial thromboplastin time (APTT) ratio were significant associations with bleeding tendencies. Of these risk factors, haematocrit and APTT ratio were two independent significant risk factors on multivariate analysis. Older patients with primary infection and younger patients with secondary infection had significant bleeding tendencies. We also verified the validity of the haematocrit levels suggested as cut-off levels for plasma leakage for the Malaysian population by Malaysian Clinical Practice Guidelines for Dengue Infection in Adults (2003).
format	Article
author	Tee, H. P. How, Soon Hin Ab Rahman, Jamalludin Mohamad Nor, Fariz Safhan M., Mohd Sapian Kuan, Yeh Chunn S., Sapari
author_facet	Tee, H. P. How, Soon Hin Ab Rahman, Jamalludin Mohamad Nor, Fariz Safhan M., Mohd Sapian Kuan, Yeh Chunn S., Sapari
author_sort	Tee, H. P.
title	Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan
title_short	Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan
title_full	Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan
title_fullStr	Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan
title_full_unstemmed	Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan
title_sort	risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in hospital tengku ampuan afzan kuantan
publisher	Malaysian Medical Associations
publishDate	2009
url	http://irep.iium.edu.my/1126/ http://irep.iium.edu.my/1126/ http://irep.iium.edu.my/1126/1/Risk_Factors_Associated_with_Development_of_Dengue.pdf
first_indexed	2023-09-18T20:08:20Z
last_indexed	2023-09-18T20:08:20Z
_version_	1777407309567229952

Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan

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