Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases

Objective: To investigate antibacterial potential of Trifolium alexandrinum Linn. (Fabaceae, Egyptian clover) against seven G+ve and eleven G– ve hospitals isolated human pathogenic bacterial strains responsible for many tropical diseases. Methods: Non-polar and polar extracts of the leaves of T. al...

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Main Authors:	Khan, Abdul Viqar, Ahmed, Qamar Uddin, Shukla, Indu, Khan,, Athar Ali
Format:	Article
Language:	English
Published:	Elsevier 2012
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/11054/ http://irep.iium.edu.my/11054/ http://irep.iium.edu.my/11054/1/Antibacterial_activity_of_leaves_extracts_of_Trifolium_alexandrinum_Linn..pdf

id	iium-11054
recordtype	eprints
spelling	iium-110542012-02-14T00:08:36Z http://irep.iium.edu.my/11054/ Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan,, Athar Ali QD Chemistry Objective: To investigate antibacterial potential of Trifolium alexandrinum Linn. (Fabaceae, Egyptian clover) against seven G+ve and eleven G– ve hospitals isolated human pathogenic bacterial strains responsible for many tropical diseases. Methods: Non-polar and polar extracts of the leaves of T. alexandrinum i.e., hexane, dichloromethane (DCM), ethyl acetate (EtOAc), methanol (MeOH) and aqueous (AQ) extracts at five different concentrations (1, 2, 5, 10 and 15 mg/ml) were prepared to evaluate their antibacterial value. NCCL standards were strictly followed to perform antimicrobial disc susceptibility test using disc diffusion method. Results: Polar extracts demonstrated significant antibacterial activity against tested pathogens. EtOAc and MeOH extracts showed maximum antibacterial activity with higher inhibition zone and were found effective against seventeen of the tested pathogens. While AQ plant extract inhibited the growth of sixteen of the test strains. EtOAc and MeOH plant extracts inhibited the growth of all seven G+ve and ten of the G-ve bacterial strains. Conclusion: Present study strongly confirms the effectiveness of crude leaves extracts against tested human pathogenic bacterial strains causing several tropical diseases. Since Egyptian clover is used as a fodder plant, it could be helpful in controlling various infectious diseases associated with cattle’s as well. Elsevier 2012-03-28 Article PeerReviewed application/pdf en http://irep.iium.edu.my/11054/1/Antibacterial_activity_of_leaves_extracts_of_Trifolium_alexandrinum_Linn..pdf Khan, Abdul Viqar and Ahmed, Qamar Uddin and Shukla, Indu and Khan,, Athar Ali (2012) Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases. Asian Pacific Journal of Tropical Biomedicine, 2 (3). pp. 189-194. ISSN 2221 1691 http://www.elsevier.com/locate/apjtb/.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan,, Athar Ali Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases
description	Objective: To investigate antibacterial potential of Trifolium alexandrinum Linn. (Fabaceae, Egyptian clover) against seven G+ve and eleven G– ve hospitals isolated human pathogenic bacterial strains responsible for many tropical diseases. Methods: Non-polar and polar extracts of the leaves of T. alexandrinum i.e., hexane, dichloromethane (DCM), ethyl acetate (EtOAc), methanol (MeOH) and aqueous (AQ) extracts at five different concentrations (1, 2, 5, 10 and 15 mg/ml) were prepared to evaluate their antibacterial value. NCCL standards were strictly followed to perform antimicrobial disc susceptibility test using disc diffusion method. Results: Polar extracts demonstrated significant antibacterial activity against tested pathogens. EtOAc and MeOH extracts showed maximum antibacterial activity with higher inhibition zone and were found effective against seventeen of the tested pathogens. While AQ plant extract inhibited the growth of sixteen of the test strains. EtOAc and MeOH plant extracts inhibited the growth of all seven G+ve and ten of the G-ve bacterial strains. Conclusion: Present study strongly confirms the effectiveness of crude leaves extracts against tested human pathogenic bacterial strains causing several tropical diseases. Since Egyptian clover is used as a fodder plant, it could be helpful in controlling various infectious diseases associated with cattle’s as well.
format	Article
author	Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan,, Athar Ali
author_facet	Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan,, Athar Ali
author_sort	Khan, Abdul Viqar
title	Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases
title_short	Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases
title_full	Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases
title_fullStr	Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases
title_full_unstemmed	Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases
title_sort	antibacterial activity of leaves extracts of trifolium alexandrinum linn. against pathogenic bacteria causing tropical diseases
publisher	Elsevier
publishDate	2012
url	http://irep.iium.edu.my/11054/ http://irep.iium.edu.my/11054/ http://irep.iium.edu.my/11054/1/Antibacterial_activity_of_leaves_extracts_of_Trifolium_alexandrinum_Linn..pdf
first_indexed	2023-09-18T20:20:25Z
last_indexed	2023-09-18T20:20:25Z
_version_	1777408069388468224

Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn. against pathogenic bacteria causing tropical diseases

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