Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria

Aim of the present study was to explore antibacterial potential of the leaves of Cycas rumphii Miq. The leaves were separately macerated with methanol and double distilled water at room temperature to obtain methanol and aqueous (AQ) extracts. The methanol extract was further successively extracted...

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Main Authors:	Khan, Abdul Viqar, Ahmed, Qamar Uddin, Khan, Athar Ali, Shukla, Indu
Format:	Article
Language:	English
Published:	Academic Journals 2011
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/11035/ http://irep.iium.edu.my/11035/ http://irep.iium.edu.my/11035/ http://irep.iium.edu.my/11035/1/Cycas_Final_Published.pdf

id	iium-11035
recordtype	eprints
spelling	iium-110352016-11-09T01:47:20Z http://irep.iium.edu.my/11035/ Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu QD Chemistry Aim of the present study was to explore antibacterial potential of the leaves of Cycas rumphii Miq. The leaves were separately macerated with methanol and double distilled water at room temperature to obtain methanol and aqueous (AQ) extracts. The methanol extract was further successively extracted with light petroleum ether (LPE), benzene (BZ), ethyl acetate (EtOAc) and methanol (MeOH) on hot water bath to get respective extracts. These extracts were evaluated for their antibacterial efficacy at six different concentrations (500 g, 1, 2, 5, 10 and 15 mg ml-1) against seven G+ve and eleven G–ve hospital isolated bacterial strains causing several tropical diseases using disc diffusion method. EtOAc and MeOH extracts showed maximum antibacterial activity against most of the bacteria taken into account. Present findings are suggestive of antibacterial agents in the leaves of C. rumphii which can be used in future for formulation of broad spectrum herbal antibacterial products. Results of present study also support various traditional uses associated with this plant which were suggestive of possible antibacterial potential of this plant. Hence, EtOAc and MeOH extracts of the leaves of C. rumphii deserve further investigations. Keywords: Cycas rumphii, crude extracts, successive extraction, antibacterial activity, Gram-positive bacteria, Gram-negative bacteria Academic Journals 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/11035/1/Cycas_Final_Published.pdf Khan, Abdul Viqar and Ahmed, Qamar Uddin and Khan, Athar Ali and Shukla, Indu (2011) Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria. Research Journal of Microbiology, 6 (10). pp. 761-768. ISSN 1816-4935 http://www.scialert.net/. DOI:10.3923/jm.2011.761.768
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
description	Aim of the present study was to explore antibacterial potential of the leaves of Cycas rumphii Miq. The leaves were separately macerated with methanol and double distilled water at room temperature to obtain methanol and aqueous (AQ) extracts. The methanol extract was further successively extracted with light petroleum ether (LPE), benzene (BZ), ethyl acetate (EtOAc) and methanol (MeOH) on hot water bath to get respective extracts. These extracts were evaluated for their antibacterial efficacy at six different concentrations (500 g, 1, 2, 5, 10 and 15 mg ml-1) against seven G+ve and eleven G–ve hospital isolated bacterial strains causing several tropical diseases using disc diffusion method. EtOAc and MeOH extracts showed maximum antibacterial activity against most of the bacteria taken into account. Present findings are suggestive of antibacterial agents in the leaves of C. rumphii which can be used in future for formulation of broad spectrum herbal antibacterial products. Results of present study also support various traditional uses associated with this plant which were suggestive of possible antibacterial potential of this plant. Hence, EtOAc and MeOH extracts of the leaves of C. rumphii deserve further investigations. Keywords: Cycas rumphii, crude extracts, successive extraction, antibacterial activity, Gram-positive bacteria, Gram-negative bacteria
format	Article
author	Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu
author_facet	Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu
author_sort	Khan, Abdul Viqar
title	Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
title_short	Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
title_full	Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
title_fullStr	Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
title_full_unstemmed	Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
title_sort	antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria
publisher	Academic Journals
publishDate	2011
url	http://irep.iium.edu.my/11035/ http://irep.iium.edu.my/11035/ http://irep.iium.edu.my/11035/ http://irep.iium.edu.my/11035/1/Cycas_Final_Published.pdf
first_indexed	2023-09-18T20:20:24Z
last_indexed	2023-09-18T20:20:24Z
_version_	1777408068208820224

Antibacterial activity of cycas rumphii miq. leaves extracts against some tropical human pathogenic bacteria

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