Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution

Cancer pain is one of the most frequently encountered pain syndromes. With the application of the World Health Organization analgesic ladder, adequate analgesia is achieved in 75% to 90% of patients. The remaining patients suffer from intractable pain requiring intrathecal analgesia. The aim of thi...

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Main Authors:	Pasutharnchat, Koravee, Tan, Kian-Hian, Mohamed, Rozilah @ Abdul Hadi, Ho, Kok-Yuen
Format:	Article
Language:	English
Published:	Academy of Medicine, Singapore 2009
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/11007/ http://irep.iium.edu.my/11007/ http://irep.iium.edu.my/11007/1/V38N11p943.pdf

id	iium-11007
recordtype	eprints
spelling	iium-110072012-02-23T04:45:09Z http://irep.iium.edu.my/11007/ Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution Pasutharnchat, Koravee Tan, Kian-Hian Mohamed, Rozilah @ Abdul Hadi Ho, Kok-Yuen R Medicine (General) Cancer pain is one of the most frequently encountered pain syndromes. With the application of the World Health Organization analgesic ladder, adequate analgesia is achieved in 75% to 90% of patients. The remaining patients suffer from intractable pain requiring intrathecal analgesia. The aim of this study was to retrospectively analyse the pain intensity before and after intrathecal analgesia and review the complications associated with the implantation and the care of the intrathecal device. Materials and Methods: We reviewed medical records of all cancer patients whose pain were managed by intrathecal catheter implants in our centre from February 2005 to August 2008. The pain intensity, medication and complications related to intrathecal catheter insertion or drug delivery were reviewed at the time before starting the intrathecal analgesia (T0) and time of discharge from the hospital/time prior to death during their stay in the hospital (Tdsc). Results: Twenty-nine patients were included. Out of these 29 patients, 86.2% had metastatic cancer. The most common indication was poor pain control. Pain intensity was reduced signifi cantly at the time of discharge from hospital (P <0.001). The number of patients with side effects from opioids decreased after intrathecal treatment. We found 4 patients with short-term catheter complications e.g. kinked or displaced catheter and catheter-related infection. Conclusion: Intractable cancer pain could be managed effectively by intrathecal analgesia with a signifi cant decrease in pain intensity and reduced opioid-related side effects. The side effects due to intrathecal opioids and complications from intrathecal catheter were minimal. Academy of Medicine, Singapore 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/11007/1/V38N11p943.pdf Pasutharnchat, Koravee and Tan, Kian-Hian and Mohamed, Rozilah @ Abdul Hadi and Ho, Kok-Yuen (2009) Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution. Annals of the Academy of Medicine, Singapore, 38 (11). pp. 943-6. ISSN 0304-4602 http://www.annals.edu.sg/pdf/38VolNo11Nov2009/V38N11p943.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Pasutharnchat, Koravee Tan, Kian-Hian Mohamed, Rozilah @ Abdul Hadi Ho, Kok-Yuen Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
description	Cancer pain is one of the most frequently encountered pain syndromes. With the application of the World Health Organization analgesic ladder, adequate analgesia is achieved in 75% to 90% of patients. The remaining patients suffer from intractable pain requiring intrathecal analgesia. The aim of this study was to retrospectively analyse the pain intensity before and after intrathecal analgesia and review the complications associated with the implantation and the care of the intrathecal device. Materials and Methods: We reviewed medical records of all cancer patients whose pain were managed by intrathecal catheter implants in our centre from February 2005 to August 2008. The pain intensity, medication and complications related to intrathecal catheter insertion or drug delivery were reviewed at the time before starting the intrathecal analgesia (T0) and time of discharge from the hospital/time prior to death during their stay in the hospital (Tdsc). Results: Twenty-nine patients were included. Out of these 29 patients, 86.2% had metastatic cancer. The most common indication was poor pain control. Pain intensity was reduced signifi cantly at the time of discharge from hospital (P <0.001). The number of patients with side effects from opioids decreased after intrathecal treatment. We found 4 patients with short-term catheter complications e.g. kinked or displaced catheter and catheter-related infection. Conclusion: Intractable cancer pain could be managed effectively by intrathecal analgesia with a signifi cant decrease in pain intensity and reduced opioid-related side effects. The side effects due to intrathecal opioids and complications from intrathecal catheter were minimal.
format	Article
author	Pasutharnchat, Koravee Tan, Kian-Hian Mohamed, Rozilah @ Abdul Hadi Ho, Kok-Yuen
author_facet	Pasutharnchat, Koravee Tan, Kian-Hian Mohamed, Rozilah @ Abdul Hadi Ho, Kok-Yuen
author_sort	Pasutharnchat, Koravee
title	Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
title_short	Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
title_full	Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
title_fullStr	Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
title_full_unstemmed	Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
title_sort	intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution
publisher	Academy of Medicine, Singapore
publishDate	2009
url	http://irep.iium.edu.my/11007/ http://irep.iium.edu.my/11007/ http://irep.iium.edu.my/11007/1/V38N11p943.pdf
first_indexed	2023-09-18T20:20:22Z
last_indexed	2023-09-18T20:20:22Z
_version_	1777408065976401920

Intrathecal analgesia in patients with cancer pain--an audit in a tertiary institution

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