Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl

Bioassay-guided isolation of methanol extract revealed that medium polar fraction of the extract contained a few compounds that inhibited the growth of dermatophytes skin caused diseases. This confirmed the traditional usages of the stem barks of Entada spiralis by Malays in the old time, as a soap,...

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Main Authors:	Mat So'ad, Siti Zaiton, Harun, Aiza, Mohd Hassan, Norazian, Che Mohd Ramli, Neni Kartini
Format:	Conference or Workshop Item
Language:	English
Published:	2011
Subjects:	QD Chemistry QR180 Immunology RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/10684/ http://irep.iium.edu.my/10684/ http://irep.iium.edu.my/10684/1/POSTER.pdf

id	iium-10684
recordtype	eprints
spelling	iium-106842012-02-23T07:11:45Z http://irep.iium.edu.my/10684/ Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl Mat So'ad, Siti Zaiton Harun, Aiza Mohd Hassan, Norazian Che Mohd Ramli, Neni Kartini QD Chemistry QR180 Immunology RS Pharmacy and materia medica Bioassay-guided isolation of methanol extract revealed that medium polar fraction of the extract contained a few compounds that inhibited the growth of dermatophytes skin caused diseases. This confirmed the traditional usages of the stem barks of Entada spiralis by Malays in the old time, as a soap, shampoo and scrub during the treatment of skin problems. Minimum inhibitory concentration of the fraction gave a significant value for the effect on selected dermatophytes which are T. rubrum, T. mentagrophytes and M. gypseum. Out of the five bioactive compounds isolated we will discuss one(1)of the compound which is proposed as a novel compound. The structural elucidation of the compound were based on spectroscopic analysis by using 1H-NMR, 13CNMR, DEPT, HMBC and HMQC. The mass spectrum, FTIR and UV were also used to support our data. From the structural elucidation,the compound is suggested as a triterpenoidal saponin which has never been reported elsewhere. 2011-11-14 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/10684/1/POSTER.pdf Mat So'ad, Siti Zaiton and Harun, Aiza and Mohd Hassan, Norazian and Che Mohd Ramli, Neni Kartini (2011) Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl. In: International Conference on Natural Products ICNP 2011, 14-16 November 2011, Putrajaya, Malaysia. http://www.icnp2011.upm.edu.my
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry QR180 Immunology RS Pharmacy and materia medica
spellingShingle	QD Chemistry QR180 Immunology RS Pharmacy and materia medica Mat So'ad, Siti Zaiton Harun, Aiza Mohd Hassan, Norazian Che Mohd Ramli, Neni Kartini Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl
description	Bioassay-guided isolation of methanol extract revealed that medium polar fraction of the extract contained a few compounds that inhibited the growth of dermatophytes skin caused diseases. This confirmed the traditional usages of the stem barks of Entada spiralis by Malays in the old time, as a soap, shampoo and scrub during the treatment of skin problems. Minimum inhibitory concentration of the fraction gave a significant value for the effect on selected dermatophytes which are T. rubrum, T. mentagrophytes and M. gypseum. Out of the five bioactive compounds isolated we will discuss one(1)of the compound which is proposed as a novel compound. The structural elucidation of the compound were based on spectroscopic analysis by using 1H-NMR, 13CNMR, DEPT, HMBC and HMQC. The mass spectrum, FTIR and UV were also used to support our data. From the structural elucidation,the compound is suggested as a triterpenoidal saponin which has never been reported elsewhere.
format	Conference or Workshop Item
author	Mat So'ad, Siti Zaiton Harun, Aiza Mohd Hassan, Norazian Che Mohd Ramli, Neni Kartini
author_facet	Mat So'ad, Siti Zaiton Harun, Aiza Mohd Hassan, Norazian Che Mohd Ramli, Neni Kartini
author_sort	Mat So'ad, Siti Zaiton
title	Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl
title_short	Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl
title_full	Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl
title_fullStr	Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl
title_full_unstemmed	Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl
title_sort	structural elucidation of a major active compounds from the stem barks of entada spiralis ridl
publishDate	2011
url	http://irep.iium.edu.my/10684/ http://irep.iium.edu.my/10684/ http://irep.iium.edu.my/10684/1/POSTER.pdf
first_indexed	2023-09-18T20:20:04Z
last_indexed	2023-09-18T20:20:04Z
_version_	1777408047350546432

Structural elucidation of a major active compounds from the stem barks of Entada spiralis Ridl

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