Granules hydroxyapatite application in fractures
In conjunction with a multi-institution research project, towards achieving the production of a locally made bone graft substitute. Hydroxyapatite (HA) granules made from local raw materials have been fabricated using a novel method (Patent (Pending) No. PI 2004 0748). The granules were chara...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AO Research Institute Davos
2008
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/10398/ http://irep.iium.edu.my/10398/ http://irep.iium.edu.my/10398/1/v016supp02a056.pdf |
| Summary: | In conjunction with a
multi-institution research project, towards
achieving the production of a locally made bone
graft substitute. Hydroxyapatite (HA) granules
made from local raw materials have been
fabricated using a novel method (Patent
(Pending) No. PI 2004 0748). The granules
were characterised both chemically and
physically and found to abide by the ASTM
F1185 - 88 (1993) specification that covers the
material requirements for HA intended for use
as surgical implants. A phase 1 clinical trial
involving the use of the granules for root socket
obliteration in young healthy adults following
tooth extraction was performed. Based on the
results of these studies, the material was
approved for a phase 2 clinical trial. The study
was approved by the University and Hospital
Clinical Ethical Committee in July 2005 |
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