An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite

We developed hydroxyapatite (HA) granules made from local raw materials (GranuMaS™), which have been fabricated using a novel method (Patent (Pending) No. PI 2004 0748). GranuMaS™ have been fully characterized using X-ray diffraction, scanning electron microscopy, energy dispersive x-ray, Four...

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Main Authors:	Zulkifly, Ahmad Hafiz, Khalid, Kamarul Ariffin, Aziz, Mohd Yusof, Mohamed Amin, Mohamed Azril, Awang, Mohd Shukrimi, Mohd Yusof, Nazri, Che Ahmad, Aminudin, Zakaria@Mohamad, Zamzuri, Fazan, Fazilah
Format:	Article
Language:	English
Published:	AO Research Institute Davos 2008
Subjects:	RD701 Orthopedics
Online Access:	http://irep.iium.edu.my/10382/ http://irep.iium.edu.my/10382/ http://irep.iium.edu.my/10382/1/v016supp02a055.pdf

id	iium-10382
recordtype	eprints
spelling	iium-103822013-12-16T00:42:25Z http://irep.iium.edu.my/10382/ An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite Zulkifly, Ahmad Hafiz Khalid, Kamarul Ariffin Aziz, Mohd Yusof Mohamed Amin, Mohamed Azril Awang, Mohd Shukrimi Mohd Yusof, Nazri Che Ahmad, Aminudin Zakaria@Mohamad, Zamzuri Fazan, Fazilah RD701 Orthopedics We developed hydroxyapatite (HA) granules made from local raw materials (GranuMaS™), which have been fabricated using a novel method (Patent (Pending) No. PI 2004 0748). GranuMaS™ have been fully characterized using X-ray diffraction, scanning electron microscopy, energy dispersive x-ray, Fourier transform infra-red spectroscopy and inductively coupled plasma methods. It has also been shown to comply with the ASTM F1185 - 88 (1993) specification standards. Biocompatibility studies have been performed on the product, which include neutral red cytotoxicity assay using cultured fibroblast and CRL-1427 osteoblast cells; MTT (Tetrazolium Salt) assay; cytotoxicity studies for apoptosis using Acridine Orange / Propidium Iodide (AO/PI) dual staining of V79 cells in DMEM; and COMET assay genotoxicity studies using L-929 (normal mouse epithelial) cells. An in vivo implantation study involving New Zealand White rabbits were carried out in the course of this study. AO Research Institute Davos 2008 Article PeerReviewed application/pdf en http://irep.iium.edu.my/10382/1/v016supp02a055.pdf Zulkifly, Ahmad Hafiz and Khalid, Kamarul Ariffin and Aziz, Mohd Yusof and Mohamed Amin, Mohamed Azril and Awang, Mohd Shukrimi and Mohd Yusof, Nazri and Che Ahmad, Aminudin and Zakaria@Mohamad, Zamzuri and Fazan, Fazilah (2008) An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite. European Cells and Materials, 16 (supp 2). p. 55. ISSN 1473-2262 http://ecmjournal.org/journal/supplements/vol016supp02/pdf/v016supp02a055.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RD701 Orthopedics
spellingShingle	RD701 Orthopedics Zulkifly, Ahmad Hafiz Khalid, Kamarul Ariffin Aziz, Mohd Yusof Mohamed Amin, Mohamed Azril Awang, Mohd Shukrimi Mohd Yusof, Nazri Che Ahmad, Aminudin Zakaria@Mohamad, Zamzuri Fazan, Fazilah An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite
description	We developed hydroxyapatite (HA) granules made from local raw materials (GranuMaS™), which have been fabricated using a novel method (Patent (Pending) No. PI 2004 0748). GranuMaS™ have been fully characterized using X-ray diffraction, scanning electron microscopy, energy dispersive x-ray, Fourier transform infra-red spectroscopy and inductively coupled plasma methods. It has also been shown to comply with the ASTM F1185 - 88 (1993) specification standards. Biocompatibility studies have been performed on the product, which include neutral red cytotoxicity assay using cultured fibroblast and CRL-1427 osteoblast cells; MTT (Tetrazolium Salt) assay; cytotoxicity studies for apoptosis using Acridine Orange / Propidium Iodide (AO/PI) dual staining of V79 cells in DMEM; and COMET assay genotoxicity studies using L-929 (normal mouse epithelial) cells. An in vivo implantation study involving New Zealand White rabbits were carried out in the course of this study.
format	Article
author	Zulkifly, Ahmad Hafiz Khalid, Kamarul Ariffin Aziz, Mohd Yusof Mohamed Amin, Mohamed Azril Awang, Mohd Shukrimi Mohd Yusof, Nazri Che Ahmad, Aminudin Zakaria@Mohamad, Zamzuri Fazan, Fazilah
author_facet	Zulkifly, Ahmad Hafiz Khalid, Kamarul Ariffin Aziz, Mohd Yusof Mohamed Amin, Mohamed Azril Awang, Mohd Shukrimi Mohd Yusof, Nazri Che Ahmad, Aminudin Zakaria@Mohamad, Zamzuri Fazan, Fazilah
author_sort	Zulkifly, Ahmad Hafiz
title	An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite
title_short	An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite
title_full	An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite
title_fullStr	An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite
title_full_unstemmed	An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite
title_sort	in vivo implantation study in new zealand white rabbits for granular hydroxyapatite
publisher	AO Research Institute Davos
publishDate	2008
url	http://irep.iium.edu.my/10382/ http://irep.iium.edu.my/10382/ http://irep.iium.edu.my/10382/1/v016supp02a055.pdf
first_indexed	2023-09-18T20:19:50Z
last_indexed	2023-09-18T20:19:50Z
_version_	1777408032385269760

An in vivo implantation study in New Zealand white rabbits for granular hydroxyapatite

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